临床微生物学档案

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Microbial Amensalism: A Natural Process for the Revival of Antibiotics

Ahtsham Ul Hassan* and Akraam Ali

Pathogenic microorganisms are developing antibiotic resistance against lifesaving drugs. Many pathogenic bacteria have now developed multi-resistance that is a significant concern over the failure of antibiotics. There is a pressing need to work on a natural amensalism strategy to cope with these resistant pathogenic strains. Pathogenic microorganisms are developing resistance against old antibiotics with the help of evolutionary mechanisms, in the same way; the microorganism that previously produced antibiotics can also upgrade their defensive antibiotic compound through evolutionary mechanisms. Microbial amensalism is a negative ecological relation that can be a pleasing strategy to upgrade failed antibiotics. Re-culturing of antibiotics producing microorganisms with antibiotic-resistant pathogenic strains can produce upgraded antibiotic compounds against these resistant strains.