Dr. Ram Babu Sharma*, Gaurav Kumar, Hitesh Thakur, Dr. Sakshi Tomar
The incorporation of a nanoemulsions system integrated into the hydrogel matrix affects better skin penetration. Nanoemulgels are known as the formulation of nanoemulsion based on hydrogel. Nanoemulgel improves the stability of a nanoemulsion formulation by lowering surface and interfacial tension, which increases the aqueous phase viscosity. Because the system has a higher viscosity than the nanoemulsion system, nanoemulgel is also known as hydrogel-thickened nanoemulsions. Hydrophobic medication delivery using nanoemulgel is extremely effective. With greater drug loading due to improved solubilizing efficiency, improved bioavailability due to superior permeability, and the ability to control drug release, it is an efficient alternative delivery technique for the treatment of many disorders. Nanogels protect biomolecules like enzymes and genetic material from destruction, while their macromolecular features let tiny molecules circulate longer and serve as a handy platform for combining therapeutic compounds. Nanoemulgel use has increased in recent years as a result of the preparation's improved acceptability among patients due to its non-greasy, convenient Spread ability, easy application, and good therapeutic and safety profile. Nanoemulgel has a strong potential of being the primary topical delivery route for lipophilic medications in the future, despite several challenges.
KeywordsNanoemulgel; Spreadability; Nanoemulsions
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