健康科学杂志

  • 国际标准期刊号: 1108-7366
  • 期刊 h 指数: 51
  • 期刊引用分数: 10.69
  • 期刊影响因子: 9.13
索引于
  • Genamics 期刊搜索
  • 中国知网(CNKI)
  • 引用因子
  • CINAHL 完整
  • 西马戈
  • 电子期刊图书馆
  • 研究期刊索引目录 (DRJI)
  • EMCare
  • OCLC-WorldCat
  • 大学教育资助委员会
  • 日内瓦医学教育与研究基金会
  • 欧洲酒吧
  • 谷歌学术
  • 夏尔巴罗密欧
  • 秘密搜索引擎实验室
分享此页面

抽象的

How the endocrine system and microbiota explain the emotions biochemistry and their impact in health

Guilherme Linhare*, Elsa S Lima, Camila P Perico, Antonio C Da Silva Filho, Camilla R De Pierri, Roberto T Raittz, Dieval Guizelini and Jeroniza N Marchaukoski

Emotional reactions stimulate neural circuits and biological pathways that produce neurotransmitters, affecting homeostasis and promoting disease. Health and emotions communicate, establishing a bidirectional cause-and-effect pathway. The composition of the microbiota also affects health and emotions, interacting through metabolites, such as short-chain fatty acids (SCFA), with the host's biochemistry. Certain genera of bacteria act in different ways on the host's homeostasis, keeping the immune system constantly vigilant and acting on the synthesis of neurotransmitters, such as serotonin and dopamine, which are responsible for well-being. When the host is in homeostasis, the synthesis of neurotransmitters is normal, which keeps the intestinal microbiota in balance. However, when the organism is out of balance, this synthesis is impaired; decreasing the concentration of the initial compounds for the production of neurotransmitters, which leads to a reduction in the concentration of neurotransmitters and exaggerated activation of the HPA axis, inducing an imbalance in the intestinal microbiota, generating dysbiosis. Due to dysbiosis, the synthesis of neurotransmitters is impaired, leading the host to develop mental disorders such as depression, anxiety and chronic stress; which contributes to the state of imbalance of the organism, harming mental and physical health. By adequately restoring the intestinal microbiota, the hyper activation of the HPA axis decreases, returning the body to homeostasis, resulting in the improvement of symptoms of depression, anxiety and chronic stress; leaving the organism healthy, both mentally and physically. Therefore, in this study we contextualize emotional research from a historical and descriptive perspective and present the main models of emotional identification. Focusing on basic emotions, we research the relationship of emotional states with the HPA axis and the microbiota, as well as how the bacteria present in the intestine affect the well-being of the host. Finally, we discuss our analysis presenting the bidirectional relationship between the endocrine system, microbiota and emotions.

免责声明: 此摘要通过人工智能工具翻译,尚未经过审核或验证