Muskan K
Chinese herbal medicines (CHMs) have been used successfully to treat infectious disorders, however it is yet unknown how well they work to cure infections caused by XDRE, or extensively drug-resistant enterobacteria. Here, we developed a retrospective multicenter study with 766 patients who had both nonfermentative bacteria (NFB) and XDRE infections to examine the efficacy of CHMs in combination with antibiotics in treating XDRE infections in a cohort of patients and to compare it to standard antibiotic monotherapy. After a 14-day course of treatment, the 547 patients who had agreed to CHMs and antibiotic therapy did so with a higher level of satisfaction than the 219 patients who had received antibiotic monotherapy. White blood cell count (WBC) and neutrophil percentage (N%) were the two main assessment indicators. The secondary evaluation indices included body temperature, breath rate, heart rate, platelets, haemoglobin, red blood cell, albumin, creatinine, glucose, and 28-day survival rates. Briefly stated, in our experience, CHMs combined with antibiotic therapy resulted in more desirable effectiveness in treating XDRE infections than antibiotic monotherapy, and CHMs may be an extremely valuable resource in the field of managing XDRE infections and illuminating the research and development of new antibiotics. Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most frequently prescribed therapeutic drug classes used globally to treat a wide range of medical conditions, including pain, inflammation, cardiovascular complications, and many other diseases. However, NSAIDs may have adverse effects, including gastroduodenal disorders. Therefore, there is a rising interest in and need for finding safe, antiulcer plant-based formulations to treat gastric ulcers brought on by NSAID use. Numerous natural plants, including Camellia sinensis, Phyllanthus emblica, Myristica malabarica, Piper betle, Picrorhiza kurroa, and others, have been the subject of extensive research. These plants' active constituents have been shown to inhibit NSAID-induced gastric ulcers through their antioxidative and immunomodulatory activity. As a result, using herbal remedies regularly may help to reduce other negative effects such stomach ulcers caused by NSAIDs.
KeywordsHerbal; Nonsteroidal
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