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Analysis of viral metagenomes in stool samples from qatari children with untreated gastroenteritis

Carolina Palmblad*

All over the world, acute gastroenteritis is a major health issue, particularly for children living in developing nations. Diarrhea is the fourth leading cause of child mortality, following intrapartum diseases, lower respiratory infections, and complications associated with preterm birth. Viruses like rotavirus, norovirus, adenovirus, and astrovirus typically cause diarrhea in children. Around the world, rotavirus infections are still a major cause of diarrhea-related death in children under the age of five. In developed nations, rotavirus vaccines already save lives, but in developing nations, they are less effective due to higher rates of early rotavirus infection transmission and inadequate vaccination coverage or accessibility. Additionally, bacteria such as Campylobacter spp. and parasites such as Cryptosporidium spp. and Giardia lamblia, AGE is primarily caused by Clostridium difficile and other bacteria.