Sanchita Rai
Postsurgical critical care unit patients are known to experience complications from systemic inflammatory response syndrome. The majority of cerebral palsy patients who receive posterior spinal fusion for neuromuscular scoliosis exhibit SIRS in the intensive care unit, according to our observations. Literature on the effects of intraoperative causes of postoperative SIRS and subsequent effects in these individuals is scarce. The goal of the study was to better understand the risk factors for SIRS in children undergoing PSF for neuromuscular scoliosis. Children who had PSF for neuromuscular scoliosis were included in this retrospective, case-control study. Patients with tracheotomy, osteogenesis imperfecta, and idiopathic scoliosis were eliminated. Depending on whether SIRS had been identified in the intensive care unit, the subjects were split into two study groups. To pinpoint factors, descriptive statistical analysis was employed. In order to further assess the independent and substantial influence of these parameters on SIRS, a regression analysis was utilised. The demographic and other preoperative characteristics did not significantly differ. However, the SIRS group received considerably more blood products overall than the non-SIRS group. When compared to the non-SIRS group, the percentage of patients who remained intubated was higher in the SIRS group. According to the regression model, patients who were not extubated had a 7.467-fold higher chance of developing SIRS than those who had been extubated. Patients who were not extubated at the conclusion of PSF surgery have a considerably greater incidence of SIRS. Additional prospective studies are required to examine the elements that hinder extubation. These individuals following their operation Cerebral palsy patients undergoing posterior spinal fusion for neuromuscular scoliosis frequently have serious comorbidities include seizures, chronic lung disease, poor nutrition, and recurrent UTIs.
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