神经病学和神经科学杂志

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Advancement of neuroimaging to improve care in sickle cell disease

Sara Stern-Nezer*

Sickle cell disease is related with moderate and expanded neurological bleakness all through the life expectancy. In individuals with sickle cell frailty (the most widely recognized and serious kind of sickle cell disease), quiet cerebral infarcts are found in excess of 33% of teenagers by age 18 years and generally 50% of youthful grown-ups by age 30 years, a considerable lot of whom have mental impedance regardless of having not many or no regular stroke risk factors. Normal physical neuroimaging in people with sickle disease can survey underlying cerebrum injury, like stroke and quiet cerebral infarcts; be that as it may, arising progressed neuroimaging strategies can give novel bits of knowledge into the pathophysiology of sickle cell infection, including experiences into the cerebral haemodynamic and metabolic donors of neurological injury. Progressed neuroimaging techniques, especially strategies that report on distorted cerebral blood stream and oxygen conveyance, have potential for triaging patients for fitting disease changing or remedial treatments before they have irreversible neurological injury, and for affirming the advantage of new treatments on mind wellbeing in clinical preliminaries.

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