国际药物开发与研究杂志

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A Review Oral Dispersible Tablets

Mukesh Chandra Sharma, Monika Leel

The oral route of drug administration is speculated as one of the most acceptable route for drug delivery. Recently the orally dispersible tablets have become the most desirable dosage forms especially for a special category of patient’s i.e. pediatric, geriatric, bedridden, mentally ill, and uncooperative patients. Quick disintegration, better patient compliance, enhanced bioavailability are some of the vital characteristics of orally dispersible tablets which makes it superior from other traditional dosage forms. It is the most prominent dosage form for the patients which face difficulty in swallowing other conventional dosage forms. Basically the ore-dispersible tablets are defined as novel solid dosage form that provide the rapid disintegration or dissolution of solid medicament to exhibit it as a solution or in suspension form before administration. Reportedly, there are numerous drug candidates, which have been successfully formulated as orally dispersible tablets and have resulted in satisfactory in-vitro as well as in-vivo results. By going through this review, a researcher can easily become familiar to this novel formulation, as this review gives a quick insight of the advantages, disadvantages, ideal characteristics, method of preparation, and evaluation parameters of the oral dispersible tablets.