国际药物开发与研究杂志

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A Review on Nanogels

C.Aparna*, N. Prasanna

The term nanogels is described as nanosized particles assembled using physically or chemically cross-linked polymer networks that swell in a suitable solvent. Nanogels are three-dimensional hydrophilic networks. These studies incorporate features for topical drug delivery, owing to their relatively high drug-encapsulation ability, consistency, tunable size, effortless preparation, insignificant toxicity, and stability in the presence of serum including stimuli responsiveness. These are water-soluble and allow immediate drug loading in aqueous media. These are synthesized using a vast number of methods which include photolithographic technique, membrane emulsification, and polymerization techniques. When nanogels are used as dermatological preparations, the thesis is that extended exposure times on  the skin and as a result, extend the duration of therapeutic potency due to the entrapment of nanoparticles in the gel matrix.

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